Linking biomedical language information and knowledge resources: GO and UMLS.

Linking Biomedical Language Information and Knowledge Resources in the 21st Century: GO and UMLS

Mapping the Gene Ontology Into the Unified Medical Language System

We have recently mapped the Gene Ontology (GO), developed by the Gene Ontology Consortium, into the National Library of Medicine's Unified Medical Language System (UMLS). GO has been developed for the purpose of annotating gene products in genome databases, and the UMLS has been developed as a framework for integrating large numbers of disparate terminologies, primarily for the purpose of provi...

Towards linking patients and clinical information: detecting UMLS concepts in e-mail

The purpose of this project is to explore the feasibility of detecting terms within the electronic messages of patients that could be used to effectively search electronic knowledge resources and bring health information resources into the hands of patients. Our team is exploring the application of the natural language processing (NLP) tools built within the Lister Hill Center at the National L...

Experiences in visualizing and navigating biomedical ontologies and knowledge bases

The biomedical domain is extensive and complex. From the perspective of information technology, this complexity translates into multiple, heterogeneous databases, offering limited interoperability. The first step towards getting a better understanding of these resources is for users to be able to visualize and navigate them. This paper presents some issues in visualizing and navigating biomedic...

Representation of roles in biomedical ontologies: a case study in functional genomics

OBJECTIVE Representing roles, i.e. functions of proteins, sequences and structures, is the cornerstone of knowledge representation in functional genomics. The objective of this study is to investigate representation of roles as functional categories or associative relations. We focus on GeneOntology (GO) and the UMLS and take examples from iron metabolism. METHODS The terms corresponding to t...